1. Rochester, Minnesota
Rochester’s claim to fame is the Mayo Clinic, the world’s first and largest non-profit group medical practice and the city's biggest employer. The clinic attracts a host of international workers and patients, which help to support the city’s numerous arts and cultural events that separate it from other cities of the same size.
Population: 108,179
Median Household Income: $62,575
Median Home Price: $163,700
